San Francisco 49ers Roster
| Name | Jersey # | Position | Height | Weight | College | Birth Date | NFL Experience | Status |
|---|---|---|---|---|---|---|---|---|
| Brett Toth | OT | 6'6" | 304 | Army | 9/1/1996 | 7 | Injured Reserve | |
| Darrick Forrest | S | 5'11" | 200 | Cincinnati | 5/22/1999 | 5 | Injured Reserve | |
| Nick Zakelj | G | 6'6" | 316 | Fordham | 6/22/1999 | 4 | Injured Reserve | |
| Brayden Willis | TE | 6'4" | 240 | Oklahoma | 11/11/1999 | 4 | Practice Squad | |
| Andrew Farmer II | DL | 6'4" | 250 | Lane College | 4/19/2000 | 2 | Injured Reserve | |
| Ricky Pearsall | WR | 6'1" | 189 | Florida | 9/9/2000 | 3 | Injured Reserve | |
| Mikail Kamara | DE | 6'1" | 260 | Indiana | 10/10/2001 | 0 | Injured Reserve | |
| Renardo Green | 0 | CB | 6'0" | 186 | Florida State | 11/9/2000 | 3 | Active |
| Deommodore Lenoir | 2 | DB | 5'10" | 200 | Oregon | 10/6/1999 | 6 | Active |
| Christian Kirk | 3 | WR | 5'11" | 200 | Texas A&M | 11/18/1996 | 9 | Injured Reserve |
| Jacob Cowing | 4 | WR | 5'9" | 171 | Arizona | 2/4/2001 | 3 | Active |
| Mike Evans | 5 | WR | 6'5" | 231 | Texas A&M | 8/21/1993 | 13 | Active |
| Malik Mustapha | 6 | S | 5'10" | 206 | Wake Forest | 6/25/2002 | 3 | Active |
| De'Zhaun Stribling | 7 | WR | 6'2" | 207 | Mississippi | 12/18/2002 | 0 | Active |
| Mac Jones | 10 | QB | 6'3" | 220 | Alabama | 9/5/1998 | 6 | Active |
| Demarcus Robinson | 11 | WR | 6'1" | 202 | Florida | 9/21/1994 | 11 | Active |
| Brandon Aiyuk | 11 | WR | 6'0" | 200 | Arizona State | 3/17/1998 | 6 | Exempt/Left Team |
| Brock Purdy | 13 | QB | 6'1" | 220 | Iowa State | 12/27/1999 | 5 | Active |
| Kurtis Rourke | 14 | QB | 6'4" | 220 | Indiana | 10/25/2000 | 1 | Active |
| Corliss Waitman | 15 | P | 6'2" | 210 | South Alabama | 7/21/1995 | 4 | Active |
| Jordan Watkins | 17 | WR | 5'11" | 196 | Mississippi | 2/15/2002 | 2 | Active |
| Eddy Piñeiro | 18 | K | 5'11" | 190 | Florida | 9/13/1995 | 9 | Active |
| Deebo Samuel Sr. | 19 | WR | 6'0" | 215 | South Carolina | 1/15/1996 | 8 | Active |
| Upton Stout | 20 | CB | 5'9" | 181 | Western Kentucky | 1/9/2002 | 2 | Active |
| Nate Hobbs | 22 | CB | 6'0" | 195 | Illinois | 6/24/1999 | 6 | Injured Reserve |
| Christian McCaffrey | 23 | RB | 5'11" | 210 | Stanford | 6/7/1996 | 10 | Active |
| Ashtyn Davis | 24 | S | 6'1" | 205 | California | 10/10/1996 | 7 | Active |
| Jack Jones | 25 | CB | 5'11" | 175 | Arizona State | 12/20/1997 | 5 | Active |
| Kaelon Black | 26 | RB | 5'10" | 208 | Indiana | 10/17/2001 | 0 | Active |
| Ji'Ayir Brown | 27 | S | 5'11" | 202 | Penn State | 1/25/2000 | 4 | Active |
| Ephesians Prysock | 28 | CB | 6'3" | 196 | Washington | 2/28/2003 | 0 | Active |
| Jordan James | 29 | RB | 5'9" | 208 | Oregon | 3/29/2004 | 2 | Active |
| Isaac Guerendo | 31 | RB | 6'0" | 221 | Louisville | 6/28/2000 | 3 | Physically Unable to Perform |
| Siran Neal | 33 | CB | 6'0" | 206 | Jacksonville State | 8/4/1994 | 9 | Active |
| Sincere McCormick | 35 | RB | 5'8" | 204 | Texas-San Antonio | 9/10/2000 | 3 | Practice Squad |
| Marques Sigle | 36 | S | 5'11" | 199 | Kansas State | 7/18/2002 | 2 | Active |
| Jalen Stroman | 38 | S | 6'0" | 203 | Notre Dame | 5/22/2003 | 0 | Practice Squad |
| Brandon Codrington | 40 | CB | 5'9" | 185 | North Carolina Central | 11/17/2000 | 3 | Practice Squad |
| Jalen Graham | 41 | LB | 6'3" | 220 | Purdue | 1/11/2001 | 3 | Practice Squad |
| Jakob Robinson | 43 | CB | 5'10" | 181 | Brigham Young | 10/10/2000 | 2 | Practice Squad |
| Kyle Juszczyk | 44 | FB | 6'2" | 235 | Harvard | 4/23/1991 | 14 | Active |
| Nick Martin | 45 | LB | 5'11" | 221 | Oklahoma State | 10/13/2002 | 2 | Injured Reserve |
| Jon Weeks | 46 | LS | 5'10" | 242 | Baylor | 2/17/1986 | 17 | Active |
| Khalid Kareem | 47 | DE | 6'4" | 255 | Notre Dame | 4/28/1998 | 4 | Active |
| Tatum Bethune | 48 | LB | 6'1" | 230 | Florida State | 2/19/2001 | 3 | Active |
| Garret Wallow | 49 | LB | 6'2" | 230 | TCU | 1/25/1999 | 6 | Active |
| Vincent Anthony Jr. | 50 | DE | 6'6" | 258 | Duke | 4/26/2004 | 0 | Practice Squad |
| Luke Gifford | 51 | LB | 6'3" | 243 | Nebraska | 8/28/1995 | 8 | Active |
| Jaden Dugger | 53 | LB | 6'5" | 242 | Louisiana | 2/26/2004 | 0 | Active |
| Fred Warner | 54 | LB | 6'3" | 230 | Brigham Young | 11/19/1996 | 9 | Active |
| Sebastian Valdez | 55 | DT | 6'3" | 301 | Washington | 8/1/2002 | 1 | Practice Squad |
| Keion White | 56 | DE | 6'5" | 285 | Georgia Tech | 1/20/1999 | 4 | Active |
| Dre Greenlaw | 57 | LB | 6'0" | 230 | Arkansas | 5/25/1997 | 8 | Active |
| Jarrett Patterson | 58 | OL | 6'4" | 310 | Notre Dame | 9/1/1999 | 4 | Active |
| Ogbo Okoronkwo | 59 | DL | 6'2" | 253 | Oklahoma | 4/24/1995 | 9 | Practice Squad |
| Foster Sarell | 61 | OT | 6'7" | 315 | Stanford | 8/28/1998 | 5 | Practice Squad |
| Austen Pleasants | 62 | G | 6'7" | 330 | Ohio | 8/22/1997 | 2 | Injured Reserve |
| Jake Brendel | 64 | C | 6'4" | 299 | UCLA | 9/10/1992 | 9 | Active |
| Drake Nugent | 66 | C | 6'1" | 300 | Michigan | 2/9/2001 | 1 | Practice Squad |
| Isaac Alarcon | 67 | OT | 6'7" | 320 | Monterrey Tech (Mexico) | 7/27/1998 | 1 | Practice Squad |
| Colton McKivitz | 68 | OT | 6'6" | 301 | West Virginia | 8/9/1996 | 7 | Active |
| Enrique Cruz Jr. | 69 | OL | 6'5" | 313 | Kansas | 8/4/2003 | 0 | Active |
| Trent Williams | 71 | OT | 6'5" | 320 | Oklahoma | 7/19/1988 | 17 | Active |
| Carver Willis | 74 | G | 6'5" | 303 | Washington | 4/20/2002 | 0 | Active |
| Connor Colby | 75 | OL | 6'5" | 309 | Iowa | 1/16/2003 | 2 | Active |
| Vederian Lowe | 76 | OT | 6'5" | 315 | Illinois | 4/17/1999 | 5 | Active |
| Dominick Puni | 77 | G | 6'5" | 313 | Kansas | 2/24/2000 | 3 | Active |
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